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Biblioteca(s): |
Embrapa Instrumentação. |
Data corrente: |
05/04/2021 |
Data da última atualização: |
10/06/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
CÔNSOLO, N. R. B.; BUARQUE, V. L. M.; SILVA, J.; POLETI, M. D.; BARBOSA, L. C. G. S.; HIGUERA-PADILLA, A.; GOMEZ, J. F. M.; COLNAGO, L. A.; GERRARD, D. E.; SARAN NETO, A.; SILVA, S. L. |
Afiliação: |
LUIZ ALBERTO COLNAGO, CNPDIA. |
Título: |
Muscle and liver metabolomic signatures associated with residual feed intake in Nellore cattle. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Animal Feed Science and Technology, v. 271, 114757, 2021. |
ISSN: |
0377-8401 |
DOI: |
https://doi.org/10.1016/j.anifeedsci.2020.114757 |
Idioma: |
Inglês |
Conteúdo: |
Identification of those cattle genetics with superior feed efficiency is necessary to increase the productivity of the entire beef industry. The aim of this study was to investigate metabolites profiling in the liver and muscle to identify physiological changes in animals in the livestock system with low or high residual feed intake. Liver and muscle were collected after slaughter from Nellore males, with high and low residual feed intake (H-RFI, n = 10 and L-RFI, n = 10, respectively). Metabolites were extracted with cold methanol/water solution (4:3 v/v). Metabolomics analyses were performed by 1D 1 H nuclear magnetic resonance. Metabolites were identified using Chenomx and analysed using MetaboAnalyst 4.0. The residual feed intake classification did not change most of animal performance traits; however, animals with lower residual feed intake presented greater carcass dressing, lower carcass fat deposition. Sixty-three compounds were identified in the liver and 31 in muscle. Coexpression network analysis was carried out and identified four metabolite network modules correlated with the phenotypic traits, indicating common metabolites with a variate important projection score that influences residual feed intake. Metabolites in liver samples was correlated with energy and protein metabolism and on muscle with fat metabolism. Differences on energetic metabolism, including of carbohydrate- and fat-correlated compounds, according to residual feed intake can be assessed by importance of concentration of citrate, isocitrate, glucose-6-phosphate, nicotinamide adenine dinucleotide + hydrogen and creatine phosphate (in liver) and choline, glycine, glycerol, malonate, glucose-6- phosphate and 3-hydroxybutyrate (in muscle). Moreover, differences on protein metabolism, MenosIdentification of those cattle genetics with superior feed efficiency is necessary to increase the productivity of the entire beef industry. The aim of this study was to investigate metabolites profiling in the liver and muscle to identify physiological changes in animals in the livestock system with low or high residual feed intake. Liver and muscle were collected after slaughter from Nellore males, with high and low residual feed intake (H-RFI, n = 10 and L-RFI, n = 10, respectively). Metabolites were extracted with cold methanol/water solution (4:3 v/v). Metabolomics analyses were performed by 1D 1 H nuclear magnetic resonance. Metabolites were identified using Chenomx and analysed using MetaboAnalyst 4.0. The residual feed intake classification did not change most of animal performance traits; however, animals with lower residual feed intake presented greater carcass dressing, lower carcass fat deposition. Sixty-three compounds were identified in the liver and 31 in muscle. Coexpression network analysis was carried out and identified four metabolite network modules correlated with the phenotypic traits, indicating common metabolites with a variate important projection score that influences residual feed intake. Metabolites in liver samples was correlated with energy and protein metabolism and on muscle with fat metabolism. Differences on energetic metabolism, including of carbohydrate- and fat-correlated compounds, according to residual feed intake can be assessed by imp... Mostrar Tudo |
Palavras-Chave: |
Muscle; Residual feed intake. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02667naa a2200289 a 4500 001 2131049 005 2022-06-10 008 2021 bl uuuu u00u1 u #d 022 $a0377-8401 024 7 $ahttps://doi.org/10.1016/j.anifeedsci.2020.114757$2DOI 100 1 $aCÔNSOLO, N. R. B. 245 $aMuscle and liver metabolomic signatures associated with residual feed intake in Nellore cattle.$h[electronic resource] 260 $c2021 520 $aIdentification of those cattle genetics with superior feed efficiency is necessary to increase the productivity of the entire beef industry. The aim of this study was to investigate metabolites profiling in the liver and muscle to identify physiological changes in animals in the livestock system with low or high residual feed intake. Liver and muscle were collected after slaughter from Nellore males, with high and low residual feed intake (H-RFI, n = 10 and L-RFI, n = 10, respectively). Metabolites were extracted with cold methanol/water solution (4:3 v/v). Metabolomics analyses were performed by 1D 1 H nuclear magnetic resonance. Metabolites were identified using Chenomx and analysed using MetaboAnalyst 4.0. The residual feed intake classification did not change most of animal performance traits; however, animals with lower residual feed intake presented greater carcass dressing, lower carcass fat deposition. Sixty-three compounds were identified in the liver and 31 in muscle. Coexpression network analysis was carried out and identified four metabolite network modules correlated with the phenotypic traits, indicating common metabolites with a variate important projection score that influences residual feed intake. Metabolites in liver samples was correlated with energy and protein metabolism and on muscle with fat metabolism. Differences on energetic metabolism, including of carbohydrate- and fat-correlated compounds, according to residual feed intake can be assessed by importance of concentration of citrate, isocitrate, glucose-6-phosphate, nicotinamide adenine dinucleotide + hydrogen and creatine phosphate (in liver) and choline, glycine, glycerol, malonate, glucose-6- phosphate and 3-hydroxybutyrate (in muscle). Moreover, differences on protein metabolism, 653 $aMuscle 653 $aResidual feed intake 700 1 $aBUARQUE, V. L. M. 700 1 $aSILVA, J. 700 1 $aPOLETI, M. D. 700 1 $aBARBOSA, L. C. G. S. 700 1 $aHIGUERA-PADILLA, A. 700 1 $aGOMEZ, J. F. M. 700 1 $aCOLNAGO, L. A. 700 1 $aGERRARD, D. E. 700 1 $aSARAN NETO, A. 700 1 $aSILVA, S. L. 773 $tAnimal Feed Science and Technology$gv. 271, 114757, 2021.
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Registros recuperados : 29 | |
1. | | VIGNATO, B. S.; COUTINHO, L. L.; CESAR, A. S. M.; POLETI, M. D.; REGITANO, L. C. de A.; BALIEIRO, J. C. de C. Comparative muscle transcriptome associated with carcass traits of Nellore cattle. BMC Genomics, v. 18, n. 506, p. 1-13, 2017.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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2. | | VIGNATO, B. S.; REGITANO, L. C. de A.; COUTINHO, L. L.; CESAR, A. S. M.; POLETI, M. D.; BALIEIRO, J. C. de C. NEDD4: a putative candidate gene for ribeye area in Nellore steers. In: WORKSHOP ON OMICS STRATEGIES APPLIED TO LIVESTOCK SCIENCE, 1., 2017, Piracicaba, SP. Proceedings... São Carlos, SP: Embrapa Pecuária Sudeste, 2017. p. 15. (Embrapa Pecuária Sudeste. Documentos, 125) Editores: Luiz Lehmann Coutinho, ESALQ/USP; Luciana Correia de Almeida Regitano, Embrapa Pecuária Sudeste; Gerson Barreto Mourão, ESALQ/USP; Aline Silva Mello Cesar, ESALQ/USP; Bárbara Silva Vignato, FZEA/USP; Mirele Daiana Poleti,...Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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3. | | KAPPELER, B. I. G.; REGITANO, L. C. de A.; POLETI, M. D.; CESAR, A. S. M.; MOREIRA, G. C. M.; GASPARIN, G.; COUTINHO, L. L. MiRNAs differentially expressed in skeletal muscle of animals with divergent estimated breeding values for beef tenderness. Molecular Biology, v. 20, n. 1, p. 2-11, 2019.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 5 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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4. | | OLIVEIRA, G. B.; KAPPELER, B. G.; CESAR, A. S. M.; POLETI, M. D.; REGITANO, L. C. de A.; COUTINHO, L. L. Micrornas expression profile and functional enrichment of Longissimus Dorsi muscle in Nellore cattle. In: CONGRESSO BRASILEIRO DE GENÉTICA, 61., 2015, Águas de Lindóia. Anais...Águas de Lindóia: Sociedade Brasileira de Genética, 2015.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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5. | | PÉRTILLE, F.; IBELLI, A. M. G.; SHARIF, M. E.; POLETI, M. D.; FRÖHLICH, A. S.; REZAEI, S.; LEDUR, M. C.; JENSEN, P.; GUERRERO-BOSAGNA, C.; COUTINHO. L. L. Putative epigenetic biomarkers of stress in red blood cells of chickens reared across different biomes. Frontiers in Genetics, 20 Nov 2020.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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6. | | OLIVEIRA, G. B. de; CESAR, A. S. M.; FELÍCIO, A. M.; KAPPELER, B. I. G.; POLETI, M. D.; REGITANO, L. C. de A.; COUTINHO, L. L. Evidence of miRNA regulation of intramuscular fat deposition in beef cattle. In: PLANT AND ANIMAL GENOME CONFERENCE, 24., 2016, San Diego. Anais... San Diego: PAG, 2016.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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7. | | VIGNATO, B. S.; COUTINHO, L. L.; CESAR, A. S. M.; POLETI, M. D.; REGITANO, L. C. de A.; BALIEIRO, J. C. de C. Gene co-expression network analysis associated with carcass traits in Nellore steers. In: ANNUAL CONFERENCE OF AUSTRALIAN MARINE SCIENCES ASSOCIATION, 57., 2017, Darwin, Australia. Proceedings... Darwin, Australia: AMSA, 2017.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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8. | | VIGNATO B. S.; COUTINHO, L. L.; POLETI, M. D.; CESAR, A. S. M.; MONCAU, C. T.; REGITANO, L. C. de A.; BALIEIRO, J. C. C. Gene co-expression networks associated with carcass traits reveal new pathways for muscle and fat deposition in Nelore cattle. Genomics, v. 20, n. 32, p. 2-13, 2019.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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9. | | OLIVEIRA, G. B. de; CESAR, A. S. M.; FELICIO, A. M.; POLETI, M. D.; REGITANO, L. C. de A.; COUTINHO, L. L. Gene network regulated by microRNAs suggests modulation of fat deposition in cattle. Journal of Animal Science, v. 94, e-suppl. 5; Journal of Dairy Science, v. 99, e-suppl. 1, p. 159, jul. 2016.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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10. | | COUTINHO, L. L.; MOROSINI, N. S.; CESAR, A. S. M.; POLETI, M. D.; REGITANO, L. C. de A.; MARGARIDO, G. R. A. Identification and characterization of euchromatic regions associated with gene expression and intramuscular fat in Nelore cattle. Journal of Animal Science, v. 96, suppl. S3, p. 233-234, 2019.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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11. | | DEFANT, H.; MEIRA, A. N.; COUTINHO, L. L.; REGITANO, L. C. de A.; POLETI, M. D.; MOREIRA, G. C. M.; PADUAN, M.; MARIANI, P.; ZERLOTINI NETO, A.; MOURÃO, G. B.; CESAR, A. S. M. Novel polymorphisms in the PLIN2 gene of Nellore cattle. Genetics and Molecular Research, v. 18, n. 3, 2019. Não paginado. Na publicação: Luciana CA Regitano, Adhemar Zerlotini. gmr16039963.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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12. | | NOVAIS, F. J. DE; YU, H.; CESAR, A. S. M.; MOMEN, M.; POLETI, M. D.; PETRY, B.; MOURÃO, G. B.; REGITANO, L. C. de A.; MOROTA, G.; COUTINHO, L. L. Multi-omic data integration for the study of production, carcass, and meat quality traits in Nellore cattle. Frontiers in Genetics, v. 13, 948240, oct. 2022. 14 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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13. | | CÔNSOLO, N. R. B.; BUARQUE, V. L. M.; SILVA, J.; POLETI, M. D.; BARBOSA, L. C. G. S.; HIGUERA-PADILLA, A.; GOMEZ, J. F. M.; COLNAGO, L. A.; GERRARD, D. E.; SARAN NETO, A.; SILVA, S. L. Muscle and liver metabolomic signatures associated with residual feed intake in Nellore cattle. Animal Feed Science and Technology, v. 271, 114757, 2021.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Instrumentação. |
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14. | | OLIVEIRA, P. S. N. de; CESAR, A. S. M.; OLIVEIRA, G. B. de; TIZIOTO, P. C.; POLETI, M. D.; DINIZ, W. J. da S.; LIMA, A. O. de; REECY, J. M.; COUTINHO, L. L.; REGITANO, L. C. de A. miRNAs related to fatty acids composition in Nellore cattle. Journal of Animal Science, v. 94, e-suppl. 5; Journal of Dairy Science, v. 99, e-suppl. 1, p. 159, jul. 2016. p. 160.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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15. | | POLETI, M. D.; SIMAS, R. C.; CESAR, A. S. M.; ANDRADE, S. C. S.; SOUZA, G. H. M. F.; CAMERON, L. C.; REGITANO, L. C. de A.; COUTINHO, L. L. Label-free MSE proteomic analysis of the bovine skeletal muscle: new approach for meat tenderness evaluation. J. Anim. Sci Vol. 94, E-Suppl. 5/J. Dairy Sci. Vol. 99, E-Suppl. 1, 2016.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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16. | | POLETI, M. D.; REGITANO, L. C. de A.; SOUSA, G. H. M. F.; CESAR, A. S. M.; SIMAS, R. C.; SILVA-VIGNATO, B.; OLIVEIRA, G. B.; ANDRADE, S. C. S.; CAMERON, L. C.; COUTINHO, L. L. Longissimus dorsi muscle label-free quantitative proteomic reveals biological mechanisms associated with intramuscular fat deposition. Journal of Proteomics, v. 179, p. 30-41, 2018.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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17. | | VIGNATO, B. S.; CESAR, A. S. M.; AFONSO, J.; MOREIRA, G. C. M.; POLETI, M. D.; PETRINI, J.; GARCIA, I. S.; CLEMENTE, L. G.; MOURÃO, G. B.; REGITANO, L. C. de A.; COUTINHO, L. L. Integrative analysis between genome-wide association study and expression quantitative trait Loci reveals bovine muscle gene expression regulatory polymorphisms associated with intramuscular fat and backfat thickness. Frontiers in Genetics, v. 13, 935238, aug. 2022. 15 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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18. | | OLIVEIRA, G. B.; REGITANO, L. C. de A.; CESAR, A. S. M.; REECY, J. M.; DEGAKI, K. Y.; POLETI, M. D.; FELICIO, A. M.; KOLTES, J. E.; COUTINHO, L. L. Integrative analysis of microRNAs and mRNAs revealed regulation of composition and metabolism in Nelore cattle. BMC Genomics, v. 19, n. 126, p. 2-16, 2018.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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19. | | POLETI, M. D.; REGITANO, L. C. de A.; SOUZA, G. H. M. F.; CESAR, A. S. M.; SIMAS, R. C.; SILVA-VIGNATO, B.; OLIVEIRA, G. B.; ANDRADE, S. C. S; CAMERON, L. C.; COUTINHO, L. L. Data from proteomic analysis of bovine Longissimus dorsi muscle associated with intramuscular fat content. Data in Brief, v. 19, p. 1314-1317, 2018.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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20. | | CARVALHO, M. E.; GASPARIN, G.; POLETI, M. D.; ROSA, A. F.; BALIEIRO, J. C. C.; LABATE, C. A.; NASSU, R. T.; TULLIO, R. R.; REGITANO, L. C. de A.; MOURÃO, G. B.; COUTINHO, L. L. Heat shock and structural proteins associated with meat tenderness in Nellore beef cattle, a Bos indicus breed. Meat Science, v. 96, n. 3, p. 1318-1324, mar. 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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Registros recuperados : 29 | |
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Nenhum registro encontrado para a expressão de busca informada. |
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